The Yankees lost a bit of a heartbreaker Thursday night, after a game-tying home run by Nick Swisher in the ninth went to waste when Dewayne Wise ended the game with a walk-off base hit in the bottom of the inning to give the White Sox a 3–2 victory.

Runs were difficult to come by as both starters gave quality outings, with Andy Pettitte allowing just one earned run in 6 and 1/3 innings. The Yankees couldn't get to Gavin Floyd, who also allowed just one run, going 7 and 2/3 and striking out 10 Yankee batters.

The game was tied after six and a half but some sloppy defense in the bottom of the seventh cost the Yankees. Jim Thome reached on an error by Pettitte to start the inning. Then with two on and one out, Carlos Quentin grounded into what might have been an inning ending double play, but a throwing error by Robinson Cano allowed Thome to come around and score the go-ahead run.

The Sox remained ahead until the Yankees were down to their last out in the ninth, but Nick Swisher took his former teammate Matt Thornton's pitch over the left field wall for a game-tying home run.

After putting two runners on base in the bottom of the ninth, Joe Girardi opted to pull Phil Hughes in favor of Phil Coke with one out. Coke got A.J. Pierzynski to fly out to center and was a strike away from getting the Yanks into extra innings, but Dewayne Wise took a 2-2 pitch right up the middle for a game-ending base hit.

The Yanks will try to bounce back tonight at 8:11 ET with Sergio Mitre taking the mound against the White Sox and Clayton Richard.

Recap records: Patrick: 28–13, Seamus: 27–18, Andrew: 7–9